The evidence on TCM is controversial and commonly criticized due to the methodological properties of scientific reports or their biased dissemination caused by language limits. It is more and more often supported by conventional medicine because its effectiveness is still debated. In addition to unconventional practices, TCM include herbal therapies and dietary supplementation. The traditional medicine of China is a health care system characterized by a unique philosophical concept of therapies and diagnostic practices. In particular, traditional Chinese medicine (TCM), which originated 2500 years ago, is widely used in Asia but is more and more often prevalent all over the world, in particular in Europe. Herbal products have been used traditionally for health purposes all over the world. officinalis fruit extracts, respectively.
Loganin and loganic acid are significant markers for standardization of C. In conclusion, the immunomodulatory effect observed in vitro may partially confirm the traditional use of Cornus fruits through alleviation of the development of diabetes-derived inflammatory complications. mas fruit, which was characterized by a significant quantity of loganic acid. officinalis fruit was higher than in the aqueous-ethanolic extract of C. The content of loganin in aqueous and aqueous-methanolic extract of C. The effect was comparable with dexamethasone. The modulatory activity of the Cornus extracts was noted in the case of secretion of IL-8 in Caco-2 cells. mas fruit showed the propensity to increase TNF- α and IL-1 β secretion.
On the other hand, the aqueous-ethanolic extract of C. officinalis fruit significantly inhibited TNF- α release by neutrophils at concentrations of 50 and 100 µg/mL. officinalis fruit, decreased IL-8 secretion by neutrophils to 54.64 ± 7.67%, 49.68 ± 6.55%, 50.29 ± 5.87% at concentrations of 5, 50, and 100 µg/mL, respectively, compared to LPS-stimulated control (100%). All standardized extracts significantly inhibited ROS production, whereas the aqueous-alcoholic extracts were particularly active inhibitors of IL-8 secretion by neutrophils. To evaluate the phytochemical differences between the studied extracts as well as to provide a method for standardization procedures, a quantitative analysis of iridoids, such as loganin, sweroside, and loganic acid, found in extracts of Cornus fruits was performed with HPLC-DAD. officinalis by an assessment of their effect on reactive oxygen species (ROS) generation in human neutrophils as well as cytokines secretion both in neutrophils (tumor necrosis factor α, TNF- α interleukin 8, IL-8 interleukin 1 β, IL-1 β) and in human colon adenocarcinoma cell line Caco-2 (IL-8).
The objective of this study was a comparison of biological activity of extracts from fruits of C. Additionally, due to the fact of mutual infiltration of Asian and European medicines, the differentiation as well as standardization of traditional prescriptions seem to be crucial for ensuring the quality of traditional products.
CORNUS MAS FEUILLE FULL
Winner of the Gold Medal award of The Pennsylvania Horticultural Society and of the Cary Award, which recognizes plants that are particularly adequate for New England, offer superior landscape appeal, are winter hardy, and are pest resistant.Edible, they may be used for syrups and preserves.īushy, this small to medium-sized flowering tree sports oval dark green leaves which turn purple in the fall, before shedding to the ground and revealing the rough, rich brown, exfoliating bark. A tough landscape tree of great beauty. The showy blooms are followed by attractive glossy red, cherry-like fruits in midsummer. In late winter to early spring, a profusion of small rounded clusters of tiny, bright yellow flowers open on the naked branches and will persist for several weeks. Remarkably ornamental and adaptable, Cornus mas (Cornelian Cherry) is a deciduous shrub or small tree providing multiseason interest.
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